Alopecia areata is an autoimmune disease mediated by T lymphocytes that results in patchy or confluent hair loss involving the scalp and body. Switched to Sulfasalazine 7 months ago on 2000mg. Docs didn’t believe it was sulfa, just stress. There are several existing treatments for alopecia areata but none of them offers stable and satisfactory results. Switched to Sulfasalazine and the hair loss stopped, but in the last couple months started losing hair again and have a bald patch on the back of my head. Promising results have been published in the past with the use of sulfasalazine in alopecia areata. A deficiency in folic acid can cause thinning and loss of hair. If medication is … Last fall, I started on 2000 mg sulfasalazine. Subject: Re: Sulfasalazine OR Methotrexate? where the heck do you buy this stuff on alldaychemist? Hair Loss Study Abstract Sulfasalazine is used as a therapy for various autoimmune conditions, including psoriasis; its effectiveness is presumed to be the result of its immunomodulatory effects. I was told it was the PsA. Sulfasalazine oral tablet is a prescription medication that's used to treat rheumatoid arthritis, juvenile rheumatoid arthritis, and ulcerative colitis. 3 … Reduced me to 1000 mg nonetheless. how much did 3 months supply cost you? People with rheumatoid arthritis (RA) may experience hair loss as a symptom of the disease or due to medication that they are taking. I’ve never experienced anything like this, am relatively young, ethnic so have lots of hair to come out (and oh it did). I don't fancy getting chronic diarrhoea or vomiting either. Alopecia areata is an unpredictable, autoimmune, hair loss disease affecting about 2% of the population. At 5 months I developed plantar fasciitis, severe fatigue, apathy, low mood and stiffness throughout my whole body. Sulfasalazine can have an affect on folic acid levels causing a deficiency. In one study, 26 patients with recalcitrant or severe alopecia areata (>40% scalp hair loss) received treatment with sulfasalazine 500 mg bid for the first month, then 1 g bid for the second month, and 1.5 g bid for a further three months. 1 The pathologic process involves a perifollicular T-cell infiltrate that causes a cytokine-mediated premature conversion of affected hairs from anagen to telogen 2 and abnormal keratinization with resultant abnormalities of the hair shaft. typed in Sulfasalazine didn't show up. Oh yes hair loss, I was worried about that one too, to be honest all the possible side effects sound pretty unpleasant, even if not hugely serious (like lung damage which does seem to be fairly rare). Forced to stop Methotrexate at week 8 due to hair loss. 4 months on 2000mg per day but no improvement but also no side effects. Major hair loss started a few months after - I mean, major. 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